Stanford - Cancer Genome Atlas Analysis of Colorectal Cancer

Elastic-net Interpretation

elastic-net interpretation

Each clinical parameter has own unique distribution of genomic signatures (Figure A). Copy number alteration features were most common in N status while methylation features were most common in the prediction of T status. Mutation was relatively common feature for MSI status compared to other clinical parameters. Inverse association is dominant in clinical stage and T status while direct association is dominant in N status and MSI (Figure B).